Adalat, which is nifedipine - belongs to hypotensive medicine with antianginalny activity. Blocking calcic channels, an active component of Adalat (nifedipine) causes decrease in intracellular concentration of ions of calcium in smooth muscle cell of intima of vessels and cardiocyte, causing vasodilatory action - in particular, on coronary vessels. As a result of decreases systolic blood pressure, falls TPR and decreases afterload on cardiac muscle. Except for normalization of a coronary blood flow, Adalat promotes pressure decrease in system of pulmonary artery, improves cerebral haemo dynamics. Long-term taking of medicine guarantees anti-atherogenous action, prevents thrombocyte aggregation.
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Adalat product description
Drug uses
Adalat is recommended to treat adult patients characterized by calcium atoms flow from the extracellular compartment to the artery cells associated with serious cardiac and vascular pathologies, such as:
- Disorders in the blood flow to the left atrium
- High blood pressure in the vessels
The mechanism of Adalat action involves relaxation of the blood vessel walls and blood flow improvement. Adalat is characterized by the fact that this anti-hypertensive agent does not affect a heartbeat.
An adequate drug application reduces pain feeling in the chest. To protect the heart, the large and small arteries, 20 and 40 mg of Adalat should be taken daily divided in two or three doses. Gradually, the daily Adalat dosage can be increased to 80 mg equally separated.
The dosing regimen is required to be adjusted under the combined treatment of hypertension, cerebrovascular disease, and low body weight.
Missed dose
Adalat pills should be taken with 2-3 hour gap between doses. If the patient takes drug 2-3 times a day at equal intervals, minor changes in the dosing regimen are allowed. If the pill intake was missed, and it is the time for the next dose, the missed pill is better to be skipped.
More information
Grapefruit juice can significantly change (increase) the pharmacodynamic properties of Adalat, so it is not recommended while taking this antihypertensive agent.
Storage
Calcium channel blocker Adalat should be stored in its original package at room temperature up to 30°C. Do not use broken or crashed pills. Protect from moisture and direct sunlight.
Adalat safety information
Warnings
Some categories of patients should take antihypertensive agent Adalat with extra caution, like, for example, the seniors, or patients with metabolic disorders (diabetes) and liver diseases (hepatitis, Budd-Chiari syndrome, and steatosis). Adalat use with drugs affecting the blood pressure (for example, Prozac, Synercid, Tagamet, and Eryc) may require the dosing regimen to be adjusted.
Disclaimer
The medical and healthcare information on the antihypertensive therapy and Adalat is intended to be used as an information resource only and should not be used for diagnostic, prognostic, and therapeutic purposes as a substitute for the cardiologist’s consultation. Using this review of Adalat as an information resource, you agree that the online pharmacy shall not be responsible for any of your actions and consequences of actions based on the use or non-use of the provided information on Adalat.
Adalat Side Effects
All adverse reactions caused by Adalat action are mild and not threatening to the patient’s health. The most common adverse reactions arisen from the use of the antianginal drug include malaise, headache, dizziness, edema, fatigue /asthenia, vasodilation, nausea, and constipation.
Sometimes such adverse reactions as mood changes, paranoid syndrome, taste perversion, anemia, arthritis, fever, nervousness, and syncope are reported as well. Few cases of gynecomastia and angioedema have been revealed in elderly patients.
Rare adverse reactions after the antianginal drug therapy were reported according to post-marketing experience. Actually, all of them were insignificant and passed in a while. Some patients taking Adalat are reported to experience irritation of the stomach and insomnia.
Zovirax in the form of a cream for external use is prescribed for the treatment of infections of the skin and mucous membranes caused by the herpes simplex virus type 1 and 2, including herpes lips. Eye ointment is used for keratitis caused by the herpes simplex virus type 1 and 2. Zovirax inside and in the form of a solution for infusion is used in the presence of herpes zoster and chicken pox;
Indications for taking Zovirax in the form of tabletsis a:treatment of infections of the mucous membranes and skin caused by the herpes simplex virus type 1 and 2, including genital herpes; treatment of patients with severe immunodeficiency (mainly, with the expanded clinical picture of AIDS, with HIV infection), who underwent bone marrow transplantation.
Advair Diskus is a drug manufactured to cope with diseases which attack bronchi and lungs. Medics prescribe it for people with COPD, pant, wheeze, dyspnea, pulmonary emphysema, and chronic bronchitis. It consists of two main components: a corticosteroid (Fluticasone) and a long-acting beta agonist (Salmeterol). The first component reduces the irritation and the swelling of lungs and bronchi. The second component makes the breathing easier. Doctors prescribe the drug for patients who need a combination treatment when one medication doesn’t work. The medicine is a part of a long-term medication as it isn’t effective in case of sudden asthma attacks.
Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.
Buspar - a partial agonist of serotonin and dopamine receptors - it has anxiolytic effect. Unlike benzodiazines buspirone does not suppress psychomotor function, or causes its small suppression; in moderate doses does not exponentiate effect of alcohol. It does not render somnolent, relaxant or antiepileptic effect.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
Doxycycline is a semi-synthetic antibiotic of a broad spectrum of tetracyclines. Causes bacteriostatic action by suppressing protein synthesis of pathogens as a result of blocking the aminoacyl transport RNA (tRNA) with the "information RNA (rRNA) complex" ribosome.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.
A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
Malegra FXT is used for the cure of erectile disorders. Its unique formula and thoughtful chemical composition allow getting a solution to the most delicate problem. The composition differs from other generics with a combination of the strongest and most effective components in the form of Sildenafil and Duloxetine which have an antidepressant effect. This combination not only stimulates the erection but also prolongs the time of sexual activity. One of the components prevents premature ejaculation, which will prolong sex for several hours.
Kamagra Polo is a drug that is considered to be Viagra’s analog. In comparison to other ED drugs, it can be taken without water because of good taste. The tablet can be chewed so that it can be taken anytime. Bad habits, penile injuries, diseases, tiredness, stress, and other factors result in erectile dysfunction. Kamagra Polo helps to get a stable and durable erection. The drug also deals with premature ejaculation and treatment of the enlarged prostate.
Forzest is one of the best erectile dysfunction drugs. Sildenafil Citrate, Tadalafil, Vardenafil, Avanafil, Dapoxetine, and other active components provoke a hard and stable erection. Forzest contains 20 mg of Tadalafil that relaxes blood vessels. Thanks to that the blood can easily stream to the genitals and cause enough pressure to make the penis erect. The drug can be also used to treat other diseases like pulmonary hypertension and diabetes.
Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.
An oxyuricide drug. It increases permeability of membranes of cells of helminths for Ca2+, it causes the generalized reduction of muscles passing into the persistent paralysis leading to death of helminths. Indications field: trematodoza; paragonimiasis; fascioliasis; giant intestinal fluke infection; snail fever intestinal; snail fever urinogenital; cestodiasis; cysticercosis; neurocysticercosis.
Propecia - an anti-hormonal drug. Used to reduce the size of the prostate gland, to increase the maximum speed of urine outflow, reducing the risk of developing acute urinary retention. The drug also turned out to be effective in the treatment of men’s alopecia.
is given to patients for treating severe acne that do not respond to other medicines
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.