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Product Description
Allopurinol is a drug that reduces the level of uric acid in the body, and also helps to dissolve urates.
The mechanism of Allopurinol's action is associated with its ability to inhibit the activity of the enzyme xanthine oxidase, which catalyzes oxidation of hypoxanthine to xanthine and its further conversion to uric acid.
Safety information
Indications for use
Allopurinol is prescribed for patients that are suffering from diseases caused by an increased level of uric acid, including podagra, urate stone disease and urate nephropathy. Allopurinol is used in the treatment of patients with secondary hyperuricemia of various genesis, primary and secondary hyperuricemia in hemoblastoses. Allopurinol 100 mg is used in pediatric practice for the treatment of patients older than 15 years suffering from urate nephropathy on treatment against leukemia, as well as patients with secondary hyperuricemia of various genesis, congenital enzymatic deficiency.
Mode of application
Allopurinol pills are intended for oral use. It is recommended to swallow tablets without chewing but drinking with a lot of water. It is advisable to take Allopurinol after meals. You have to drink a large amount of fluid to maintain a normal diuresis, in case of necessity you can also alkalinize urine. The duration of treatment and dose of the drug Allopurinol is determined by the doctor. The daily dose is calculated taking into account the levels of uric acid in the plasma. The average daily dose is 100-300 mg of allopurinol.
The daily dose can be assigned at one time. It is recommended to start therapy with a minimum dose (100 mg per day) and, if necessary to adjust it. Correction of the dose of allopurinol is carried out 1 time in 1-3 weeks, taking into account the level of uric acid in the plasma.
The average maintenance dose is 200-600 mg of allopurinol per day. In some cases, high-dose treatment (600-800 mg of allopurinol per day) may be required.
Side effects
Allopurinol rarely causes side effects. Mostly at the beginning of treatment, patients may develop gout attacks. In rare cases arise: agranulocytosis, thrombocytopenia, aplastic anemia, angioimmunoblastnaya lymphadenopathy, leukocytosis, leukopenia, eosinophilia, elevated liver enzymes, acute cholangitis, xanthine stones, granulomatous hepatitis, liver necrosis, hyperglycemia, hyperlipidemia, depression, peripheral neuritis, ataxia, headache, paralysis, neuropathy, decrease in visual acuity, retinal degeneration, cataract, changes in sense of taste, decreased blood pressure, bradycardia, erectile dysfunction, infertility, gynecomastia, Stevens-Johnson syndrome, urticaria, purpura, exfoliative dermatitis, Lyell's syndrome, vasculitis, epidermal necrolysis, joint pain, fever, anaphylactic shock, angioedema, sore throat, vomiting of blood, disease, steatorrhea, disorders stool, nausea, alopecia, hair
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.
An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.
Stromectol - a medical preparation that effectively cope with many kinds of parasites. It is used to treat lice, scabies, as well as onchocerciasis (river blindness) and other nematodes in humans and animals. It is applied externally and internally, depending on the disease.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Strattera - the drug with an international non-proprietary name of the active substance - Atomoxetine, it is intended as a sympathomimetic agent for the prevention and treatment of attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older, adolescents and adults.
Sildalist - sildenafil plus tadalafil tablet, a preparation manufactured by Cipla Inc. One red colored rectangular pill is equivalent to 1 pill of sildenafil100mg and 1 pill of tadalafil 20mg mixed together. This is the most potent product to stop erectile malady. The task of Sildalist tablets is to make penis ready for a sex as soon as the user comes into a state of sexual arousal.
Blocker of H1-histamine receptors, also expresses antimuscarinic and antiserotonin activity. Anti-allergic effect is most vivid in respect of itching dermatoses. Used symptomatically during allergic reactions.
Prednisolone is a synthetic analogue of the adrenal cortex secreted by the hormones cortisone and hydrocortisone. Unlike cortisone and hydrocortisone, prednisolone does not cause a noticeable delay in sodium and water, and only slightly increases the release of potassium. The drug has a pronounced anti-inflammatory, antiallergic, anti exudative, anti-shock, antitoxic effect.
Elimite is a brand-name drug that has generic variants as Permethrin. It’s produced in the form of the topical agent. It’s a cream that kills parasites, head lice and Sarcoptesscabiei in particular. The drug first paralyzes and then kills parasites and exterminates their eggs. The cream can be used in pediatrics and by adults. It’s safe and is recommended to be removed in the bath or shower. People should remove it in eight to fourteen hours. Sometimes the treatment needs to be repeated.