Thiol derivative, a competitive hypoxanthine antagonist, has an immunosuppressive and cytostatic effect. It is used for prevention of rejection reaction in kidney transplantation, treatment of rheumatoid arthritis, chronic active hepatitis, SLE, dermatomyositis, periarteritis nodosa, acquired hemolytic anemia, gangrenous pyoderma, psoriasis, Crohn's disease, ulcerative colitis and myopathy.
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Imuran Product Description
Drug Uses
Imuran is an immunosuppressive agent used for the suppression of immune responses in the treatment of autoimmune diseases or after organ transplantation. Imuran tablets can be used alone, or as a part of combined immunomodulatory therapy.
As an immunosuppressive antimetabolite, Imuran is approved as:
- Prevention of rejection of transplanted organs and improved survival after organ transplantation (including for medical management of renal, cardiac and hepatic transplant recipients).
- Management of active, severe, inflammatory and chronic autoimmune diseases of joints, skin, skeletal muscles, blood cells, arteries, liver and other organs and body systems.
Imuran maintenance dose to prevent transplant rejection ranges from 1mg to 4mg (once a day). The maintenance daily doses of Imuran for patients with autoimmune diseases vary from 1mg to 3mg (as a single or two divided doses).
Missed dose
If you take Imuran several times a day and skip a regular dose, take it as soon as you remember. Do not double Imuran dose and do not take extra immunosuppressive drugs to make up the missed dose.
More Information
To prevent transplant rejection, Imuran can be used together with other immunosuppressive agents. For symptomatic treatment of autoimmune diseases, Imuran can be used together with glucocorticoids (GCs) or non-steroidal anti-inflammatory drugs (NSAIDs).
Storage
Imuran tablets should be protected from direct sunlight and stored in a dry place, at room temperature not exceeding 30°C.
Imuran Safety Information
Warnings
Drugs suppressing immune responses (such as, Imuran) may increase the risk of developing malignancies. Patients with high risk of malignancies should be prescribed with Imuran only if the benefits of immunosuppressive therapy outweigh the potential risks.
Disclaimer
Data about immunosuppressive therapy represented in this Imuran review is intended only for general information. This information in no case does not constitute an offer of a substitute for the immunologist’s professional medical advice or diagnosis of immune diseases. The online pharmacy shall not be held responsible for any damages resulting from the use of information about transplantation, autoimmune diseases and Imuran.
Imuran Side Effects
Imuran adverse reactions are reversible and disappear when decreasing the dose or duration of immunosuppressive therapy. The most severe adverse reactions of Imuran are hematologic and gastrointestinal disorders, such as leucopenia, infection, anemia, nausea, vomiting, hepatic toxicity, diarrhea, fever, malaise, vasculitis or muscle pain. Less often, Imuran may cause skin rashes, hair loss, fever, joint pain, steatorrhea, infections (e.g. viral, fungal and bacterial) or exanthem.
Zovirax in the form of a cream for external use is prescribed for the treatment of infections of the skin and mucous membranes caused by the herpes simplex virus type 1 and 2, including herpes lips. Eye ointment is used for keratitis caused by the herpes simplex virus type 1 and 2. Zovirax inside and in the form of a solution for infusion is used in the presence of herpes zoster and chicken pox;
Indications for taking Zovirax in the form of tabletsis a:treatment of infections of the mucous membranes and skin caused by the herpes simplex virus type 1 and 2, including genital herpes; treatment of patients with severe immunodeficiency (mainly, with the expanded clinical picture of AIDS, with HIV infection), who underwent bone marrow transplantation.
Advair Diskus is a drug manufactured to cope with diseases which attack bronchi and lungs. Medics prescribe it for people with COPD, pant, wheeze, dyspnea, pulmonary emphysema, and chronic bronchitis. It consists of two main components: a corticosteroid (Fluticasone) and a long-acting beta agonist (Salmeterol). The first component reduces the irritation and the swelling of lungs and bronchi. The second component makes the breathing easier. Doctors prescribe the drug for patients who need a combination treatment when one medication doesn’t work. The medicine is a part of a long-term medication as it isn’t effective in case of sudden asthma attacks.
Sinequan - antidepressant, which is taken as prescribed by the doctor in case of the following indications: depression, anxiety and sleep disturbance in neuroses, alcoholism, organic diseases of the central nervous system, psychoneurotic disorders with anxiety, depression, psychotic depression (including the involutionary, reactive depressive phase of manic-depressive Psychosis). In general therapeutic practice - duodenal ulcer, dumping syndrome, premenstrual syndrome, chronic pain in cancer patients, skin itching, chronic idiopathic urticaria.
Buspar - a partial agonist of serotonin and dopamine receptors - it has anxiolytic effect. Unlike benzodiazines buspirone does not suppress psychomotor function, or causes its small suppression; in moderate doses does not exponentiate effect of alcohol. It does not render somnolent, relaxant or antiepileptic effect.
Cipro - the antimicrobic broad-spectrum agent derivative of fluroquinolone, suppresses bacterial DNA gyrase, breaks DNA synthesis, growth and division of bacteria; causes prominent morphological changes and fast death of a bacterial cell. It effects bactericidal at gram-negative organisms during a dormant period and deletion, on gram-positive microorganisms - only during deletion. During taking Cipro there is no parallel development of resistance to other antibiotics, which do not belong to group of inhibitors of a gyrase that does it highly effective in relation to bacteria which can be steady, for example to aminoglycosides, penicillin, cephalosporins, tetracyclines and many other antibiotics.
Sumycin - An antibiotic based on tetracycline, a brand of such pharmaceutical companies as Bristol-Myers Squibb, Apothecon, Par Pharmaceutical.
Cefixime is a medicine intended for the treatment of acute and chronic bronchitis, bacterial bronchitis, middle ear inflammation, pharyngitis and tonsillitis, bacterial infections of the urinary tract, cystitis, urethritis, pyelonephritis, cerivitis.
Doxycycline is a semi-synthetic antibiotic of a broad spectrum of tetracyclines. Causes bacteriostatic action by suppressing protein synthesis of pathogens as a result of blocking the aminoacyl transport RNA (tRNA) with the "information RNA (rRNA) complex" ribosome.
A thiazide diuretic of the average intensity, applied in arterial hypertension, edema syndrome of different origin, gestosis and diabetes insipidus. Reduces reabsorption of Na+ at the level of the Henle loop cortical segment, without affecting its segment lying in the medulla of the kidney that detects a weaker diuretic effect compared with furosemide.
A selective calcium channel blockers; a derivative of dihydropyridine; has a vasodilating, antihypertensive, antianginal effect. Has a high selective activity against smooth muscle of the arterioles. Prescribed to the patients with hypertension, angina pectoris (voltage, vasospastic, unstable with the ineffectiveness of beta-blockers and nitrates), Raynaud's syndrome (as a symptomatic drug).
Malegra FXT is used for the cure of erectile disorders. Its unique formula and thoughtful chemical composition allow getting a solution to the most delicate problem. The composition differs from other generics with a combination of the strongest and most effective components in the form of Sildenafil and Duloxetine which have an antidepressant effect. This combination not only stimulates the erection but also prolongs the time of sexual activity. One of the components prevents premature ejaculation, which will prolong sex for several hours.
Kamagra Polo is a drug that is considered to be Viagra’s analog. In comparison to other ED drugs, it can be taken without water because of good taste. The tablet can be chewed so that it can be taken anytime. Bad habits, penile injuries, diseases, tiredness, stress, and other factors result in erectile dysfunction. Kamagra Polo helps to get a stable and durable erection. The drug also deals with premature ejaculation and treatment of the enlarged prostate.
Forzest is one of the best erectile dysfunction drugs. Sildenafil Citrate, Tadalafil, Vardenafil, Avanafil, Dapoxetine, and other active components provoke a hard and stable erection. Forzest contains 20 mg of Tadalafil that relaxes blood vessels. Thanks to that the blood can easily stream to the genitals and cause enough pressure to make the penis erect. The drug can be also used to treat other diseases like pulmonary hypertension and diabetes.
Aciphex - the medicine, normalizing acidity of a stomach, inhibitor of a proton pomp. It is prescribed at gastroduodenal ulcer in the exacerbation phase, gastroesophageal reflux disease; states which are characterized by pathological hyper secretion including Zollinger-Ellison syndrome. In combination with bactericide - Helicobacter pylori eradication at patients with gastric ulcer or chronic gastritis; treatment and prevention of recurrence of an ulcer at patients with gastric ulcer related to Helicobacter pylori.
An oxyuricide drug. It increases permeability of membranes of cells of helminths for Ca2+, it causes the generalized reduction of muscles passing into the persistent paralysis leading to death of helminths. Indications field: trematodoza; paragonimiasis; fascioliasis; giant intestinal fluke infection; snail fever intestinal; snail fever urinogenital; cestodiasis; cysticercosis; neurocysticercosis.
Propecia - an anti-hormonal drug. Used to reduce the size of the prostate gland, to increase the maximum speed of urine outflow, reducing the risk of developing acute urinary retention. The drug also turned out to be effective in the treatment of men’s alopecia.
is given to patients for treating severe acne that do not respond to other medicines
Haldol antipsychotic remedy, butyrophenone derivative. It has a powerful antipsychotic effect, moderate sedation. The mechanism of antipsychotic action of haloperidol is associated with the blockade of dopamine receptors in the mesocortex and limbic system.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.