It is a sulfonamide diuretic that is pharmacologically related to thiazide diuretics. The medicine inhibits sodium reabsorption in the cortical segment of the kidneys. It increases the excretion of sodium and chlorides in the urine and the excretion of potassium and magnesium, thus increasing diuresis. The antihypertensive effect of the active components appears at doses at which the diuretic effect is insignificant. Moreover, its antihypertensive effect persists even in patients with hypertension.
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The tablets are aimed at reducing the ability of smooth muscle vessels to contract and to stimulate the synthesis of prostaglandin PGE2 and prostacyclin PGI2 (vasodilator and platelet aggregation inhibitor).
Product Description
The pills increase the excretion of sodium in the urine, and to a lesser extent the release of magnesium and potassium. Thus the action of diuresis becomes faster. The effect of the drug persists even in people with hypertension. The medicine operates at the level of the vessels. It decreases the contractility of the muscles of blood vessels, stimulates indapamide in blood vessels, and reduces left ventricular hypertrophy.
According to studies that had different duration-short, medium and long, it has been determined that the pills do not affect the metabolism of lipids, triglycerides, low-density lipoprotein cholesterol and high-density lipoprotein; they do not influence the metabolism of carbohydrates, even in patients with hypertension and diabetes. If the recommended dose is exceeded, then the therapeutic effect of the components of the tablet will not be greater and the frequency of adverse reactions will increase. One should not increase the dose if the treatment is ineffective.
Safety Information
The tablets are not recommended and are contraindicated for people who have a high sensitivity to them or any other excipients. The pills are not recommended for people with severe renal insufficiency, with severe liver function disorders, with hypokalemia. It is not advised to combine medicine with lithium at a high level of its concentration in plasma may appear. They will be together with the symptoms of overdose with a salt-free diet. If you are appointed a diuretic, it is necessary to conduct a thorough study of the level of lithium in the blood.
If you take pills with the drugs mentioned above, there is a risk of gastric arrhythmia and gastric tachycardia or hypokalemia. Before taking this combination of tablets you need to check the level of potassium and correct it to a normal level if necessary. It is also necessary to control the level of plasma electrolytes. If there is hypokalemia, you need to take drugs that do not cause wave burst arrhythmia.
The best time for taking remedy is in the morning, 1 tablet (0.0015 g), without grinding, without chewing and washing with a ½ cup of water. The maximum daily dose - 1 tablet (0.0015 g).
Side Effects
A large number of negative effects (clinical or laboratory parameters are known to depend on the dose of the pill) can cause such adverse reactions as:
- Thrombocytopenia, hemolytic anemia, leukopenia, agranulocytosis;
- Dizziness (vertigo), fatigue, headache, paresthesia; fainting.
- Arrhythmia, hypotension; paroxysmal ventricular tachycardia;
- Vomiting; nausea, constipation, dry mouth; pancreatitis;
- Renal failure.
Patients with hypersensitivity who had a high predisposition to allergies and asthma, maculopapular rash; purpura; angioedema and/or urticaria, toxic epidermal necrolysis.
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.
Super ED Trial Pack (6 Viagra + 6 Cialis + 6 Levitra) - a set sampler of Super ED Trial Pack generics which was created at numerous requests of customers. The set comprises 6 tablets (of big popularity) for solution of men's intimate problems. The set consist of: Viagra 100 mg, Cialis (20 mg) and Levitra (20 mg) that is production of well known Indian companies. All medicine of the Super ED Trial Pack set contain optimum doses of active agent and therefore you can take it for several times. Besides, it is quite possible to save money, having divided each tablet into parts.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
Allopurinol - a drug that promotes the excretion of uric acid and the removal of urinary calculi.
Promethazine reduces the permeability of capillaries, swelling of the mucous membranes, itching. Has adrenolytic, moderate peripheral and central cholinolytic action. Inhibits histamine-N-methyltransferase, blocks central histamine H3 receptors. Oppresses the central nervous system, has a sedative, anxiolytic, antipsychotic and hypnotic effect, lowers body temperature. Reduces the excitability of the vestibular receptors, eliminates dizziness. Has antiemetic effect.
Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.
An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.
Stromectol - a medical preparation that effectively cope with many kinds of parasites. It is used to treat lice, scabies, as well as onchocerciasis (river blindness) and other nematodes in humans and animals. It is applied externally and internally, depending on the disease.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Strattera - the drug with an international non-proprietary name of the active substance - Atomoxetine, it is intended as a sympathomimetic agent for the prevention and treatment of attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older, adolescents and adults.
Sildalist - sildenafil plus tadalafil tablet, a preparation manufactured by Cipla Inc. One red colored rectangular pill is equivalent to 1 pill of sildenafil100mg and 1 pill of tadalafil 20mg mixed together. This is the most potent product to stop erectile malady. The task of Sildalist tablets is to make penis ready for a sex as soon as the user comes into a state of sexual arousal.
Blocker of H1-histamine receptors, also expresses antimuscarinic and antiserotonin activity. Anti-allergic effect is most vivid in respect of itching dermatoses. Used symptomatically during allergic reactions.
Prednisolone is a synthetic analogue of the adrenal cortex secreted by the hormones cortisone and hydrocortisone. Unlike cortisone and hydrocortisone, prednisolone does not cause a noticeable delay in sodium and water, and only slightly increases the release of potassium. The drug has a pronounced anti-inflammatory, antiallergic, anti exudative, anti-shock, antitoxic effect.
Elimite is a brand-name drug that has generic variants as Permethrin. It’s produced in the form of the topical agent. It’s a cream that kills parasites, head lice and Sarcoptesscabiei in particular. The drug first paralyzes and then kills parasites and exterminates their eggs. The cream can be used in pediatrics and by adults. It’s safe and is recommended to be removed in the bath or shower. People should remove it in eight to fourteen hours. Sometimes the treatment needs to be repeated.
