Tofranil is a drug that is very sensitive to the form of depressive disorder (glycoem depressive disorder, depressive phase of bipolar infections, depressive disorder, migraine, depression, dysthymia;
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Product Description
Tofranil is one of the main representatives of tricyclic antidepressants. Due to its high efficiency and clinical value, it has been used since the 50s until today. In addition to antidepressant has a stimulating effect. It is assigned for depressive states of various etiologies, including: asthenodepressive syndrome, depression (endogenous, involutional, climacteric, reactive, alcoholic), depressive states in psychopathy and neuroses, panic disorder, functional enuresis in children.
Safety information
Tofranil is assigned usually for an oral intake (after mealth), starting at 0.75-0.1 g per day, then gradually the dosage is increased (daily by 0.025 g) and finally comes to 0.2-0.25g per day. With the onset of an antidepressant effect, increasing the dose is not recommended. The treatment - on average - lasts 4-6 weeks, then the dose is gradually reduced and the treatment is switched to maintenance therapy (with 0.025 g 1-4 times a day).
The constant medical supervision of patients with suicidal tendencies is mandatory. During the treatment with tofranil, all alcoholic beverages are restricted. It is recommended to control the cellular composition of peripheral blood and liver function. During the treatment of patients with diabetes, the correction of doses of oral hypoglycemic drugs is necessary. During the initial period of therapy, we must abandon the management of vehicles and carry out potentially hazardous activities.
Contraindications: hypersensitivity, hepatic-renal failure, IHD, tachycardia, congestive heart failure, early post-infarction period, propensity to convulsions, schizophrenia, epilepsy, glaucoma, prostate adenoma, bladder atony, pregnancy, children's age (up to 6 years).
Side effects
On the part of the nervous system and sensory organs: headache, dizziness, excessive sedation, paresthesia, tremor, convulsions, dysarthria, impaired coordination of movements, sleep disturbance, agitation, hallucinations, disruption of accommodation.
On the part of the cardiovascular system and blood system (hematopoiesis, hemostasis): tachycardia, arrhythmia, orthostatic hypotension, leukocytosis or leukopenia, agranulocytosis.
On the part of the digestive tract: dryness in the oral cavity, constipation, hepatitis.
On the part of the genitourinary system: delay urination, gynecomastia, galactorrhea, decreased libido, impotence.
Other: weight gain, photosensitivity, hair loss, fever, hyper-hidrosis.
Tricor - is a hypolipidemic agent, has an uricosuric and antiplatelet effect. In combination with diet therapy, the drug is prescribed for a long-term treatment, the effectiveness of which must be periodically checked by determining serum lipid levels.
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Keppra - antiepileptic drug, the mechanism of action is unclear, it does not alter normal synaptic transmission. Effective in both focal and epilepsy (epileptiform manifestations, photo paroxysmal reaction).
Synthroid finds use as a hormone-regulating agent for managing low levels of triiodothyronine/thyroxine. It also has a pronounced therapeutic effect on goiters of certain types. Synthroid often accompanies surgeries and other medical means of treating thyroid cancer. The drug compensates for the insufficient production of thyroid hormones by standing in their place as a synthetic substitution. Compensations of this kind help the patient’s body to restitute the normal rate of metabolism. Synthroid also helps to fight obesity due to its ability to remove the initial thyroid gland-related causes as such.
