Sustiva is an antiviral agent. A non-nucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). It is based on efavirenz and is named like Sustiva by Bristol-Myers Squibb and United Drug.
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Sustiva (Efavirenz) product description
Sustiva is a drug belonging to the group of non-nucleoside reverse transcriptase inhibitors. It is widely used in order to cure the HIV infection. Introduced in 1998, Efavirenz being combined with two reverse transcriptase suppressor showed greater efficacy than protease inhibitors and nevirapine. The studies that were conducted in inSouth Africa among 2817 HIV-positive adult patients demonstrated the benefits of efavirenz before nevirapine. Sustiva as a whole has proved to be a more effective and safe drug. Sustiva is able to inhibit the advancement of HIV up to 144 weeks. The advantages of Sustiva include the fact that it can be taken 1 time per day. Studies have shown that in 95% of patients 48 weeks after the onset of Sustiva, there was a decrease in viral load and an increase in CD4 T-lymphocyte count. This medical remedy has good tolerability. At the beginning of the therapy, there are adverse reactions on the CNS, but after a few weeks, their severity can be significantly reduced. The advised dosage of Efavirenz is 600 mg once a day (tablets can be as per 200 or 600 mg). It is desirable to take the dose before a bedtime.
Sustiva safety information
Sustiva is not prescribed to pregnant, because it has teratogenic properties. During the medical care, it is necessary to choose an adequate way of contraception. Against the background of Sustiva, there was a significant reduction in the contraceptive effect of the use of implants with etonogestrel. This medical agent helps to lower the concentrations of etonogestrel, levonorgestrel, and norelgestromin in the blood.
Do not administrateSustiva concomitantly with astemizole or ergot alkaloids, cisapride or midazolam, as well as with terfenadine, and triazolam, or even with oral contraceptives. The simultaneous consumption of saquinavir and amprenavir with efavirenz is possible if this combination enhances ritonavir (otherwise serum concentrations are inadequate). It is not recommended to eat efavirenz together with food containing a large amount of fat. As this affects the absorption of the drug, lowering its concentration. If the medical care with efavirenz was preceded by the treatment with protease inhibitors, it is advised that, during the first week of the regiment, efavirenz continues to receive a protease suppressor. When using lopinavir, reinforced atazanavir, indinavir, rifabutin, methadone simultaneously with efavirenz, the adjustment of the dosages of these drugs is required.
Sustiva side effects
The administration of Sustiva is most often accompanied by adverse effects on the CNS. Often there are undesirable effects such as the nightmares, the feeling of dizziness, drowsiness, feeling of confusion, the incoherence of mind, impaired concentration, insomnia, depersonalization. The patient before the administration of efavirenz should remember that he or she would rather not engage in potentially hazardous motions that may need one to be better concentrated than usual. In particular, during the regiment of treatment with a help of Sustiva, it is not allowed to drive the car or operate any machinery.
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Starlix - an oral synthetic hypoglycemic drug. A medicine based on nateglinide for the treatment of diabetes, which helps to control blood sugar levels. This medicine helps your body to react better to the insulin produced by your pancreas.
Starlix is used in conjunction with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.
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Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Furosemide - «Loopback" diuretic; causes quickly coming, severe and short-term diuresis. Has natriuretic and chloro effects, increases clearance of K+, Ca2+, Mg2+. It is taken at edematous syndrome, cirrhosis, diseases of kidneys, heavy course of arterial hypertension and hypercalcemia.
Capoten suppresses activity of angiotensin-converting-enzyme therefore angiotensin-I turns into angiotensin II - substance which has strong vasoconstrictive action. Capoten reduces secretion of Aldosteronum in suprarenal cortex, at the same time the delay of sodium and water in an organism decreases. Capoten slows down process of bradykinin destruction and promotes increase of E2 prostaglandin, and also nitrogen oxide that causes vasodilating action. Thanks to these effects it is decreased the increased arterial pressure, the general peripheric resistance decreases, pressure in the right auricle, in a small circle of blood circulation decreases and cordial emission increases.
A semi-synthetic antibiotic from the macrolides group for oral administration. The list of indications includes: infections of the upper and lower respiratory tract (pharyngitis, bronchitis, pneumonia, bacterial infection in COPD, panbronchiolitis, bronchiectasis), respiratory tract (tonsillitis, sinusitis, otitis media), skin and soft tissues (erysipelas, phlegmon, furuncles, folliculitis, impetigo, pyoderma), urinary tract (urethritis, endometritis, cervicitis, vaginitis, including sexually transmitted infections, except gonorrhea), oral cavity (periodontitis), bones (periostitis, chronic osteomyelitis); scarlet fever, diphtheria, whooping cough, trachoma, migratory erythematous rash, brucellosis.
Forxiga is the drug produced in the form of tablets. Tablets belong to SGLT2 inhibitors. Its main purpose is to reduce the level of blood sugar. It helps the kidney to remove glucose from the organism and excrete it during urination. It also helps to lose weight. Patients use the tablets to treat type II diabetes and get rid of the additional weight that is the result of the health disorder. The drug can be taken alone as a monotherapy or as an additional treatment. It doesn’t fit people with diabetes I.
The antifungal agent which has activity against dermatophytes, yeasts, dimorphic fungi and eumycetes. It is also active against staphylococci and streptococci. The therapeutical indications of the drug include: mycoses of the gastrointestinal tract, eyes, genital organs, chronic recurrent vaginal candidiasis, dermatomycosis, onychomycosis, Candida, folliculitis, dermatophytosis, systemic fungal infections (blastomycosis, candidiasis, paracoccidioides, coccidioidomycosis, cryptococcosis, histoplasmosis, hromomikoz, sporotrichosis, paronychia, fungal sepsis, fungal pneumonia); leishmaniasis; tinea versicolor, prevention of fungal infections in patients with a high risk of their development. The mechanism of action is inhibition of fungal membrane ergosterol synthesis and the violation of the cell wall permeability.
It has a direct influence on muscles, mainly of arterial vessels over nitric receptor situated in blood vessels. Its active component is transformed into oxide in smooth muscles that effect prompts the activity of guanylate cyclases. It is crucial for the creation of cyclic guanosine monophosphate (relaxation mediator). The drug influence the processes in the central vascular system and heart activity. The nature and force of the influence of nitroglycerin on the cardiac organ and vessels depend on the cooperation of essential actions.
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Florinef is a brand name of Fludrocortisone. It is a corticosteroid produced to treat adrenogenital syndrome (also called Apera-Galle syndrome), Addison's disease, orthostatic hypotension, cerebral salt wasting syndrome, and adrenal insufficiency. The drug replenishes the deficiency of hormones of the adrenal cortex. 1 tablet contains 0.1 mg of fludrocortisone acetate. It participates in the metabolism, including mineral and carbohydrate one. The drug causes the retention of sodium ions and promotes the excretion of potassium.
Blocks the final stage of HCl secretion, reducing basal and stimulated secretion, regardless of the nature of the stimulus. Prescribed for gastric ulcer and duodenal ulcer in acute phase, erosive-ulcerative esophagitis, reflux esophagitis, Zollinger-Ellison syndrome, stress ulcers of the gastrointestinal tract; eradication of Helicobacter pylori within a combination therapy, non-ulcer dyspepsia.
An antimicrobial bactericide - synthetic derivative of nitroimidazole. Used in urethritis, vaginitis, intestinal amoebiasis, liver amoebiasis, giardiasis.
Cytoxan antineoplastic medicine of alkylating action, it has also immunodepressive effect. It is taken for treatment of small-celled lung cancer, ovarian cancer, cancer of a neck and uterus, cancer of bladder, prostate cancer, blastoma and leucosis.
is given to patients for treating severe acne that do not respond to other medicines
Azulfidine - a medicine with antimicrobic and antiinflammatory properties. It is taken at ulcer colitis, an ulcer proctitis, a pseudorheumatism, Crohn's disease. After reception Sulfasalazinum - it is observed the normal intestinal microflora, and as result of the molecule of active ingredient breaks up to compound components: sulphapyridine and 5-aminosalicylic acid. These substances have antibacterial and antiinflammatory activity. Antiinflammatory effect of 5-aminosalicylic acid thanks to low ability to absorption is defined generally in walls of a large intestine. Sulphapyridine has generally systemic antiinflammatory effect due to better absorption.
Etodolac - has an anti-inflammatory, analgesic, antipyretic effect. The medicine is prescribed in case of rheumatoid arthritis, ankylosing spondylitis, arthrosis with pain syndrome and restriction of movements, acute and chronic osteoarthritis.
Elavil - antidepressive medicine. Renders also some analgesic, H2-histamineblocking and antiserotonin action, promotes elimination of bedwetting and reduces appetite. It is taken at Depressions (especially with anexiety, agitation and sleep disorders, including children's age, endogenous, involutional, reactive, neurotic, medicinal, at organic lesions of a brain, alcoholic abstinence), schizophrenic psychoses, mixed emotional frustration, behavior disorders, night enuresis, nervous bulimia, chronic pain syndrome.
Feldene - the drug used for treatment of inflammatory and degenerative diseases of musculo-skeletal system. NSAIDS, renders antiinflammatory, analgestic, antiaggregant and febrifugal action. Not selectively suppresses COX1 and COX2. The analgetic effect is observed in 30 min. after peroral intake, the antiinflammatory effect occurs by the end of the 1 (first) week of treatment by Feldene. After a single dose of Feldene it acts during 24 h.
Antibiotic with antitumor activity obtained from the Streptomyces caespitosus fungus. It inhibits DNA synthesis, in high concentrations it inhibits the synthesis of protein and RNA. Has a relatively weak immunosuppressive activity.
The drug therapeutic indications include: esophageal cancer, stomach cancer, pancreatic cancer, liver cancer, cancer of the bile ducts, cancer of the colon and rectum, breast cancer, cervical cancer, endometrial cancer, vulvar cancer, non-small cell lung cancer, mesothelioma, cancer of the renal pelvis and ureter, bladder cancer, prostate cancer, malignant tumors of the head and neck, chronic myelocytic leukemia.
It is a combined drug with a fixed solution of dosages of active substances -lisinopril and amlodipine. The first one is a blocker of the enzyme peptidyl. The second hormone activates the discharge of aldosterone by the cortex. ACE restriction leads to reduced absorption of angiotensin.
Since the mechanism is based on the inhibition of the aldosterone and chemosin systems. The pill reduces an arterial pressure in people with high tension as well.
Phenergan is an antiallergic, topical anesthetic, antihistamine, antipruritic, antiemetic, hypnotic, sedative on the basis of Prometnazine.
Female Viagra - women's viagra. Active component Sildenafil citrate, 100 mg which is a part of Women's Viagra at the same time is an active inhibitor of phosphodiesterase (PDE-5) which increases a blood stream to generative organs that promotes blood-impregnation of vulvar lips and the woman's clitoris. In parallel activity of mucous glands increases, providing lubricant in vagina. As a result, a woman gets a natural orgasm and lack of dryness in vagina at sexual intercourse. Drug duration - up to 5 hours. It is necessary to take Female Viagra - women's viagra in a dosage no more than 100 mg (1 tablet) a day and in 30-50 minutes prior to the planned sexual intercourse.
The drug made of herbs is used in the treatment of varicose veins, thrombophlebitis, hemorrhoids, proctitis. Its active components reduce varicose veins and prevent their formation. In general, it has a healing effect on veins, improves blood circulation, strengthens the walls of venous vessels, relieves inflammation and swelling, reduces pressure in the venous system of the liver. Pilex has an anti-inflammatory effect on the nodes of the venous system, accelerates blood stagnation, lowers cholesterol, relieves discomfort, itching and pain as well as inflammation of the rectum, hemorrhoids.
