Prednisolone is a synthetic analogue of the adrenal cortex secreted by the hormones cortisone and hydrocortisone. Unlike cortisone and hydrocortisone, prednisolone does not cause a noticeable delay in sodium and water, and only slightly increases the release of potassium. The drug has a pronounced anti-inflammatory, antiallergic, anti exudative, anti-shock, antitoxic effect.
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Product description
Prednisolone is a synthetic analogue of the adrenal cortex secreted by the hormones cortisone and hydrocortisone. Prednisolone is 4-5 times more active than cortisone and 3-4 times as compared with hydrocortisone when administered orally. Unlike cortisone and hydrocortisone, prednisolone does not cause a noticeable delay in sodium and water, and only slightly increases the release of potassium. The drug has a pronounced anti-inflammatory, antiallergic, antiexudative, anti-shock, antitoxic effect.
Indications
- Collagenosis, rheumatism, infectious nonspecific polyarthritis (inflammation of several joints), bronchial asthma, acute lymphoblastic and myeloblastic leukemia (malignant blood tumor originating from the blood-forming bone marrow cells), infectious mononucleosis;
- An acute infectious disease that occurs with a high temperature rise, an increase in palatine lymph nodes, a liver), neurodermatitis (skin disease due to impairment of the central nervous system), eczema (a neuro-allergic skin disease characterized by dizzying, itchy inflammation) and other skin diseases, various allergic diseases, Addison's disease (decreased adrenal function), acute adrenocortical insufficiency, hemolytic anemia (decrease in hemoglobin in the blood due to increased erythrocyte decay), glomerulonephritis (kidney disease), acute pancreatitis (inflammation of the pancreas);
- To prevent shock and collapse (a sharp drop in blood pressure) during surgical interventions;
- To suppress the rejection reaction in homotransplantation (transplantation from one person to another) organs and tissues;
- Allergic, chronic and atypical conjunctivitis (inflammation of the outer shell of the eye) and blepharitis (inflammation of the eyelid edges); Inflammation of the cornea with intact mucosa;
- Acute and chronic inflammation of the anterior segment of the choroid, sclera (opaque part of the fibrous membrane of the eyeball) and episcleras (the outer loose layer of the sclera, in which the blood vessels pass);
- Sympathetic inflammation of the eyeball (inflammation of the anterior part of the choroid of the eye due to penetrating injury of the other eye);
- After injuries and operations with prolonged irritation of eyeballs.
- Severe forms of hypertension (persistent rise in blood pressure),
- diabetes mellitus and Itenko-Cushing's disease;
- Pregnancy, circulatory failure III stage,
- acute endocarditis (inflammation of the internal cavities of the heart),
- psychosis,
- nephritis (inflammation of the kidneys),
- osteoporosis,
- peptic ulcer of the stomach and duodenum,
- recent surgery,
- syphilis,
- active tuberculosis,
- senile age.
- obesity,
- hirsutism (excessive hair in women, manifested by the growth of beard, mustache, etc.),
- the appearance of acne,
- menstrual irregularity,
- osteoporosis,
- the symptom complex of Itenko-Cushing (obesity, accompanied by a decrease in sexual function, increased fragility of the bones due to Increased ulceration of the adrenocorticotropic hormone of the pituitary gland),
- ulceration of the digestive tract,
- perforation of the unrecognized ulcer (the appearance of a through wall or gut wall defect at the site of the ulcer),
- hemorrhagic pancreatitis (inflammation of the pancreas flowing with a hemorrhage into her body),
- hyperglycemia (increase of blood sugar level),
- a decrease in resistance to infections,
- increased coagulability of blood,
The dose is set individually.
Safety information
Contrindications
During pregnancy, especially in the first trimester, prednisolone should be administered with an extreme caution.
Side effects
In case of prolonged use:
- obesity,
- hirsutism (excessive hair in women, manifested by the growth of beard, mustache, etc.),
- the appearance of acne,
- menstrual irregularity,
- osteoporosis,
- the symptom complex of Itenko-Cushing (obesity, accompanied by a decrease in sexual function, increased fragility of the bones due to Increased ulceration of the adrenocorticotropic hormone of the pituitary gland),
- ulceration of the digestive tract,
- perforation of the unrecognized ulcer (the appearance of a through wall or gut wall defect at the site of the ulcer),
- hemorrhagic pancreatitis (inflammation of the pancreas flowing with a hemorrhage into her body),
- hyperglycemia (increase of blood sugar level),
- a decrease in resistance to infections,
- increased coagulability of blood, mental disorders.
Vermox - anthelminthic drug of a wide spectrum of action. The most effective for Enterobius vermicularis, Trichuris trichiura, Ascaris lumbricoides, Ancylostoma duodenale, Necator americanus, Strongyloides stercoralis, Taenia solium, Echinococcus granulosus, Echinococcus multilocularis, Trichinella spiralis, Trichinella nativa, Trichinella nelsoni.
Causing an irreversible violation of glucose utilization, depletes glycogen stores in helminth tissues, interferes with the synthesis of cellular tubulin, and also inhibits the synthesis of ATP.
Super ED Trial Pack (6 Viagra + 6 Cialis + 6 Levitra) - a set sampler of Super ED Trial Pack generics which was created at numerous requests of customers. The set comprises 6 tablets (of big popularity) for solution of men's intimate problems. The set consist of: Viagra 100 mg, Cialis (20 mg) and Levitra (20 mg) that is production of well known Indian companies. All medicine of the Super ED Trial Pack set contain optimum doses of active agent and therefore you can take it for several times. Besides, it is quite possible to save money, having divided each tablet into parts.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Cialis Professional - effective tablets for improvement of erection. They begin to work in 15 minutes from the moment of taking and actions for 36 hours. They can cause not less than 10, but no more than 16 erections. The medicine increases duration of sexual intercourse. The tablets are successfully used for reduction of time for recovery of erection after ejaculation.
Cialis Super Active is a generic drug, against erectile dysfunction, containing 20 mg of tadalafil. The tablets in this series have a gel inside. This form allows the active substance, Tadalafil, to immediately enter the blood, thus providing an immediate effect. The result from the Cialis Super Active tablets appears after 5 minutes! The action lasts for two days. The drug is safe and has virtually no contraindications.
Glucophage - guanyl guanidine, hypoglycemic medicine for peroral takein. At patients with a diabetes mellitus reduces concentration of glucose in blood by oppression of gluconeogenesis in a liver, reduction of absorption of glucose from GIT and increase of its utilization in tissues. Stabilizes or reduces a body weight.
The antibiotic produced by Streptomyces lincolniensis, has a bacteriostatic effect. Suppresses protein synthesis of bacteria due to reversible binding to the 50S subunit of ribosomes, disrupts the formation of peptide bonds.
It is active against gram-positive cocci Streptococcus spp., including Streptococcus pneumoniae); Haemophilus influenzae; Bacillus anthracis, Mycoplasma spp., Bacteroides spp., Corynebacterium diphtheriae, Clostridium perfringens, Clostridium tetani.
Bactrim - a combined drug, containing two active ingredients: sulfanamide drug sulfamethoxazole and derivative of diaminopyrimidine - trimethoprimum. Colibacillus life activity oppresses that leads to reduction of synthesis of thymine, riboflavinum, niacin, etc. group B vitamins in intestines. Duration of therapeutic effect makes 7 years.
An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.
Stromectol - a medical preparation that effectively cope with many kinds of parasites. It is used to treat lice, scabies, as well as onchocerciasis (river blindness) and other nematodes in humans and animals. It is applied externally and internally, depending on the disease.
Viagra - Active ingredient - Sildenafil, 100 mg. Effect of "Viagra" is based on significant increase of blood stream to penis. Begins to work in 30 minutes, the effect lasts for 4-5 hours. Most of men can take this generic viagra every day. Millions of men worldwide cannot be mistaken, choosing Viagra!
Hydrea - antineoplastic medicine, antimetabolite, slows down DNA synthesis. It is used for treatment of acute and chronic myelogenous leukemia, osteomyelofibrosis, erythremia, essential thrombocythaemia, thrombocytosis associated with myeloproliferative syndrome, lymphogranulomatosis, melanoma, ovarian cancer, horionepitelioma of uterus, tumor of the head and the neck, tumor of brain, an acute lymphoblastic leukosis at children, a colon cancer, a prostate cancer, cancer of a lung, cancer of a neck of uterus (for increase in efficiency of radiation therapy).
Strattera - the drug with an international non-proprietary name of the active substance - Atomoxetine, it is intended as a sympathomimetic agent for the prevention and treatment of attention deficit hyperactivity disorder (ADHD) in children 6 years of age and older, adolescents and adults.
Sildalist - sildenafil plus tadalafil tablet, a preparation manufactured by Cipla Inc. One red colored rectangular pill is equivalent to 1 pill of sildenafil100mg and 1 pill of tadalafil 20mg mixed together. This is the most potent product to stop erectile malady. The task of Sildalist tablets is to make penis ready for a sex as soon as the user comes into a state of sexual arousal.
Blocker of H1-histamine receptors, also expresses antimuscarinic and antiserotonin activity. Anti-allergic effect is most vivid in respect of itching dermatoses. Used symptomatically during allergic reactions.
Elimite is a brand-name drug that has generic variants as Permethrin. It’s produced in the form of the topical agent. It’s a cream that kills parasites, head lice and Sarcoptesscabiei in particular. The drug first paralyzes and then kills parasites and exterminates their eggs. The cream can be used in pediatrics and by adults. It’s safe and is recommended to be removed in the bath or shower. People should remove it in eight to fourteen hours. Sometimes the treatment needs to be repeated.
